The Ferrari 275 S, a sports racing car produced by Ferrari in 1950, marked the debut of a new V12 engine designed by Aurelio Lampredi. This engine was a large displacement alternative to the 1.5 L Colombo V12 used in the Ferrari 125 F1, aligning with Formula One's regulations for naturally aspirated engines. Only two examples of the 275 S were made, both with Touring barchetta bodywork, and neither survives in its original form. Both 275 S cars participated in the 1950 Mille Miglia, driven by teams Alberto Ascari with Senesio Nicolini and Luigi Villoresi with Pasquale Cassani, but neither finished due to transmission issues. Despite limited success in races, the engine demonstrated its potential and was soon utilized in the single-seater Ferrari 275 F1, fulfilling its original design purpose.